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Michael K E Schäfer Selected Research

Adducted Thumbs) Syndrome Shuffling Gait Aphasia MASA (Mental Retardation

1/2021Amelioration of the abnormal phenotype of a new L1 syndrome mouse mutation with L1 mimetics.
2/2012Pathomechanistic characterization of two exonic L1CAM variants located in trans in an obligate carrier of X-linked hydrocephalus.
10/2010L1 syndrome mutations impair neuronal L1 function at different levels by divergent mechanisms.

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Michael K E Schäfer Research Topics

Disease

13Traumatic Brain Injuries (Traumatic Brain Injury)
04/2022 - 06/2014
5Brain Injuries (Brain Injury)
01/2021 - 01/2017
5Gliosis
11/2020 - 01/2017
4Inflammation (Inflammations)
04/2021 - 01/2018
3Adducted Thumbs) Syndrome Shuffling Gait Aphasia MASA (Mental Retardation
01/2021 - 10/2010
2Encephalitis (Encephalitis, Rasmussen)
01/2021 - 01/2017
2Body Weight (Weight, Body)
10/2020 - 01/2019
2Neuralgia (Stump Neuralgia)
01/2020 - 11/2019
2Pain (Aches)
01/2020 - 11/2017
2Peripheral Nerve Injuries
01/2020 - 11/2017
2Seizures (Absence Seizure)
01/2018 - 12/2017
2Wounds and Injuries (Trauma)
01/2017 - 06/2014
2Neurodevelopmental Disorders
10/2010 - 07/2010
1Shock
04/2021
1Ischemic Stroke
01/2021
1Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage)
01/2021
1Hypersensitivity (Allergy)
10/2020
1Charcot-Marie-Tooth Disease (Peroneal Muscular Atrophy)
10/2019
1Polyneuropathies (Polyneuropathy)
10/2019
1Neurologic Manifestations (Neurological Manifestations)
01/2018
1Chronic Pain
11/2017
1Frontotemporal Dementia (Semantic Dementia)
11/2017
1Autistic Disorder (Autism)
11/2017
1Mood Disorders (Mood Disorder)
01/2017
1Breast Neoplasms (Breast Cancer)
01/2017
1Ischemia
08/2014
1Heart Arrest (Cardiac Arrest)
08/2014
1Stroke (Strokes)
08/2014
1Mitochondrial Diseases (Mitochondrial Disease)
04/2014
1Nervous System Diseases (Neurological Disorders)
02/2012
1Carcinoma (Carcinomatosis)
07/2010
1Intellectual Disability (Idiocy)
07/2010
1Paraplegia (Spastic Paraplegia)
07/2010
1Neoplasms (Cancer)
08/2008
1Neurodegenerative Diseases (Neurodegenerative Disease)
07/2006
1Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
07/2006

Drug/Important Bio-Agent (IBA)

6Proteins (Proteins, Gene)FDA Link
04/2021 - 08/2014
5ProgranulinsIBA
01/2021 - 01/2017
4Neural Cell Adhesion Molecule L1 (L1 Cell Adhesion Molecule)IBA
01/2021 - 07/2010
3Glycoproteins (Glycoprotein)IBA
01/2021 - 01/2017
2Glial Fibrillary Acidic ProteinIBA
04/2021 - 08/2019
2Small Interfering RNA (siRNA)IBA
11/2019 - 07/2006
2GTP Phosphohydrolases (GTPases)IBA
10/2019 - 07/2006
2InterferonsIBA
09/2019 - 08/2019
2Pentylenetetrazole (Metrazol)IBA
01/2018 - 12/2017
1Triglycerides (Triacylglycerol)IBA
04/2022
1phosphatidylethanolamineIBA
04/2022
1GABA-A Receptor AgonistsIBA
01/2022
1Aminobutyrates (Aminobutyric Acid)IBA
01/2022
1Midazolam (Versed)FDA LinkGeneric
01/2022
1BenzodiazepinesIBA
01/2022
1ElectrolytesIBA
04/2021
1Facilitative Glucose Transport Proteins (Glucose Transporter)IBA
04/2021
1Lipocalin-2IBA
04/2021
1SolutionsIBA
04/2021
1BESIBA
04/2021
1Starch (Cornstarch)IBA
04/2021
1Messenger RNA (mRNA)IBA
04/2021
1OsteopontinIBA
01/2021
13- (formylhydroxyamino)- 2- (3- phenyl- 1- propyl)butanoic acid (2,2- dimethyl- 1- methylcarbamoyl- 1- propyl)amideIBA
01/2021
1Biomarkers (Surrogate Marker)IBA
01/2021
1Aspartic Acid (Aspartate)FDA Link
01/2021
1Tretinoin (Retinoic Acid)FDA LinkGeneric
11/2020
1HMGB1 Protein (HMG1)IBA
11/2020
1Caspase 3 (Caspase-3)IBA
11/2020
1EndocannabinoidsIBA
10/2020
1RNA (Ribonucleic Acid)IBA
01/2020
1Aurora Kinase BIBA
01/2020
1Aurora KinasesIBA
01/2020
1SETD7 inhibitor PFI-2IBA
11/2019
1Adenosine Triphosphate (ATP)IBA
10/2019
1Angiotensin Receptors (Angiotensin II Receptor)IBA
01/2019
1Gonadal Steroid Hormones (Sex Hormones)IBA
01/2019
1candesartanIBA
01/2019
1Carrier Proteins (Binding Protein)IBA
01/2018
1perlecanIBA
01/2018
1LigandsIBA
01/2018
1Heparan Sulfate Proteoglycans (Heparan Sulfate Proteoglycan)IBA
01/2018
1ZincIBA
11/2017
1zinc-binding protein (zinc binding protein)IBA
11/2017
1Interleukin-10 (Interleukin 10)IBA
01/2017
1Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
01/2017
1Aromatase InhibitorsIBA
01/2017
1Interleukin-6 (Interleukin 6)IBA
01/2017
1CytokinesIBA
01/2017
1Nerve Growth Factor Receptor (Nerve Growth Factor Receptor, Low Affinity)IBA
10/2015
1Oxygen (Dioxygen)IBA
08/2014
1Neuroprotective AgentsIBA
06/2014
1Plasminogen Activator Inhibitor 1IBA
06/2014
1Hypoxia-Inducible Factor 1IBA
06/2014
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
06/2014
12-MethoxyestradiolIBA
06/2014
1Glutathione (Reduced Glutathione)IBA
04/2014
1Reactive Oxygen Species (Oxygen Radicals)IBA
04/2014
1CalnexinIBA
02/2012
1Neural Cell Adhesion Molecules (Neural Cell Adhesion Molecule)IBA
02/2012
1IntegrinsIBA
08/2008
1Guanine Nucleotide Exchange Factors (Guanine Nucleotide Exchange Factor)IBA
07/2006

Therapy/Procedure

1Resuscitation
04/2021
1Therapeutics
01/2017